The New York Times takes note of the ukulele's renewed popularity:
Suddenly there's something irresistible again about ukuleles.Again? The ukulele has never been resistible.
The Times article suggests several reasons for renewed interest in the uke, including Jake Shimabukuro's virtuoso performance of "While My Guitar Gently Weeps." Oddly though, the Times doesn't mention George Harrison's own possible influence. The scenes of George with uke in hand in the documentary The Beatles Anthology (1995) prompted me (and, I suspect, others) to pick up the instrument. (George's uke can be heard at the end of the Beatles' "Free as a Bird.")
And in case you're wondering: yes, it's possible to play "Smells Like Teen Spirit" on the ukulele.
While my ukulele gently weeps